EP-1387: High local control with 4D-IGRT based SBRT for stage I NSCLC: a retrospective study

Pretreatment SUVmax as a Marker for Progression-Free Survival in Stage I NSCLC Treated With SBRT.

Dose-Escalated Robotic SBRT for Stage I–II Prostate Cancer

Stereotactic body radiotherapy (SBRT) is the precise external delivery of very high-dose radiotherapy to targets in the body, with treatment completed in one to five fractions. SBRT should be an ideal approach for organ-confined prostate cancer because (I) dose-escalation should yield improved rates of cancer control; (II) the unique radiobiology of prostate cancer favors hypofractionation; and...

Single Institution’s Dosimetry and IGRT Analysis of Prostate SBRT

BACKGROUND AND PURPOSE To report single institution's IGRT and dosimetry analysis on the 37 Gy/5 fraction prostate SBRT clinical trial. MATERIALS/METHODS The IRB (Duke University Medical Center) approved clinical trial has treated 28 patients with stage T1-T2c prostate cancer with a regimen of 37 Gy in 5 fractions using IMRT and IGRT protocols since 2009. The clinical trial protocol requires ...

Stage I NSCLC: elucidating the prognostic factors.

Non-small cell lung cancer (NSCLC) remains the number one cause of cancer related deaths. While early stage NSCLC portends the best survival following complete surgical resection, as many as 37% of patients with stage I disease have recurrence within 5 years of diagnosis. Several studies have investigated the role of adjuvant chemotherapy for early stage disease. However, the benefit of adjuvan...

Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer: A Small Academic Hospital Experience

PURPOSE/OBJECTIVE(S) Stereotactic body radiation therapy (SBRT) has been shown to have increased local control and overall survival relative to conventional external beam radiation therapy in patients with medically inoperable stage I non-small cell lung cancer (NSCLC). Excellent rates of local control have been demonstrated both in clinical trials and in single-center studies at large academic...